Serum (2006): cast, story & where to watch
2006 · Film · ★ 3.5

Released in 2006, Serum is a horror and science fiction film directed by Steve Franke, running about 89 minutes. “The moment you are injected, the chaos begins.” — that tagline sets the tone.
What it’s about. While searching for a "cure all" serum, Dr. Edward Kanopolus, "Dr. K", is being pressured for results by the pharmaceutical company funding the project. With time running out, tragedy and desperation drive him to make decisions that will jeopardize the lives of everyone around him and ultimately unleash a terrifying monster on a killing spree.
Who’s in it. Serum stars Derek Phillips as Eddie, Dennis O'Neill as Richard, Liz Cardenas Franke as Sarah (as Lizabeth Cardenas) and David H. Hickey as Dr. K, among others.
How it landed. With an audience score of 3.5/10, Serum has proved divisive with audiences.
Where to watch. In US you can stream it on Troma NOW. See the full, country-by-country breakdown on our where to watch Serum page.
If you liked it. Fans of Serum tend to enjoy Psycho, The Silence of the Lambs, The Shining and Alien.
Frequently asked
- Where can I watch Serum (2006)?
- In US, Serum is available to stream on Troma NOW. Availability varies by country — check our where-to-watch page for every region.
- Is Serum worth watching?
- Serum holds an audience score of 3.5 out of 10, and is a strong pick if you enjoy horror and science fiction. Reactions are mixed, so it may depend on taste.
- Who stars in Serum?
- Serum stars Derek Phillips, Dennis O'Neill, Liz Cardenas Franke, David H. Hickey and Bill Sebastian.
- When was Serum released?
- Serum was released in 2006, with a runtime of about 89 minutes.