Side Effects (2005): cast, story & where to watch

2005 · Film · ★ 5.9

Side Effects poster

Released in 2005, Side Effects is a comedy, drama and romance film directed by Kathleen Slattery-Moschkau, running about 90 minutes. “Love is a drug!” — that tagline sets the tone.

What it’s about. America! Built on a better pill. Karly Hert has spent the last ten years selling drugs. Legally, that is. Karly is a pharmaceutical sales representative. She sells pills to doctors. She makes lots of money. She has a company car. She has a nice fat expense account. But there's a growing pit in Karly's stomach. Something isn't right behind the scenes at big pharma. Based on the director's decade working directly for the industry.

Who’s in it. Side Effects stars Katherine Heigl as Karly Hert, Lucian McAfee as Zach Danner, David Durbin as Dan and Dorian DeMichele as Jacqueline, among others.

How it landed. With an audience score of 5.9/10, Side Effects has drawn a solid, mixed-to-positive response.

Where to watch. Streaming options change often. See the full, country-by-country breakdown on our where to watch Side Effects page.

If you liked it. Fans of Side Effects tend to enjoy Forrest Gump, Parasite, Life Is Beautiful and Fight Club.

Frequently asked

Where can I watch Side Effects (2005)?
Streaming, rental and purchase options for Side Effects change frequently. Check our where-to-watch page for the latest availability in your country.
Is Side Effects worth watching?
Side Effects holds an audience score of 5.9 out of 10, and is a strong pick if you enjoy comedy, drama and romance. Reactions are mixed, so it may depend on taste.
Who stars in Side Effects?
Side Effects stars Katherine Heigl, Lucian McAfee, David Durbin, Dorian DeMichele and Temeceka Harris.
When was Side Effects released?
Side Effects was released in 2005, with a runtime of about 90 minutes.