Common Side Effects (2025): cast, story & where to watch
2025 · Series · ★ 8.4
Released in 2025, Common Side Effects is an animation, drama, comedy and sci-fi & fantasy series.
What it’s about. Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.
Who’s in it. Common Side Effects stars Dave King as Marshall Cuso (voice), Emily Pendergast as Frances Applewhite (voice), Mike Judge as Rick Kruger (voice) and Martha Kelly as Agent Harrington (voice), among others.
How it landed. With an audience score of 8.4/10, Common Side Effects sits among the best-reviewed titles in the catalogue.
Where to watch. In US you can stream it on HBO Max Amazon Channel, YouTube TV, Adult Swim and HBO Max and rent or buy it from Amazon Video, Apple TV Store, Google Play Movies and Fandango At Home. See the full, country-by-country breakdown on our where to watch Common Side Effects page.
If you liked it. Fans of Common Side Effects tend to enjoy Rick and Morty, Demon Slayer: Kimetsu no Yaiba, Attack on Titan and Attack on Titan: No Regrets.
Frequently asked
- Where can I watch Common Side Effects (2025)?
- In US, Common Side Effects is available to stream on HBO Max Amazon Channel, YouTube TV and Adult Swim, and rent or buy from Amazon Video, Apple TV Store and Google Play Movies. Availability varies by country — check our where-to-watch page for every region.
- Is Common Side Effects worth watching?
- Common Side Effects holds an audience score of 8.4 out of 10, and is a strong pick if you enjoy animation, drama, comedy and sci-fi & fantasy. Most viewers rate it highly.
- Who stars in Common Side Effects?
- Common Side Effects stars Dave King, Emily Pendergast, Mike Judge, Martha Kelly and Joseph Lee Anderson.
- When was Common Side Effects released?
- Common Side Effects was released in 2025.