Lindsay Lohan

Cady Heron

Rachel McAdams

Regina George

Lacey Chabert

Gretchen Wieners

Amanda Seyfried

Karen Smith

Lizzy Caplan

Janis Ian

Daniel Franzese

Damian Leigh

Jonathan Bennett

Aaron Samuels

Tina Fey

Sharon Norbury

Tim Meadows

Principal Ron Duvall

Amy Poehler

June George

Ana Gasteyer

Betsy Heron

Neil Flynn

Chip Heron

Rajiv Surendra

Kevin Gnapoor

Elana Shilling

Spelling Girl

Graham Kartna

Homeschooled Boy

Ely Henry

Homeschooled Boy

David Aherne

Homeschooled Boy

Ayo Agbonkpolo

African Warrior

Molly Shanahan

Kristen Hadley

Jonathan Malen

Kristen Hadley's Boyfriend

Jeff Moser

Farting Guy

Miranda Edwards

Michigan Girl

Les Porter

Chemistry Teacher

Eve Crawford

English Teacher

Jack Newman

History Teacher

Michelyn Emelle

Music Teacher

Bathsheba Garnett

German Teacher

Ky Pham

Trang Pak

Danielle Nguyen

Sun Jin Dinh

Daniel DeSanto

Jason

Alisha Morrison

Lea Edwards

Chris Anton

Huge Guy

Dwayne Hill

Coach Carr

Diego Klattenhoff

Shane Oman

Jan Caruana

Emma Gerber

Wai Choy

Tim Pak

Julia Chantrey

Amber D'Alessio

Jacky Chamberlain

Giselle Sgro

Olympia Lukis

Jessica Lopez

Stefanie Drummond

Bethany Byrd

Kristen Bone

Short Girl

Jessie Wright

Five-Year-Old Cady

Tyson Fennell

Nfume

Stephan Dickson

Animal Dancer

Andreja Punkris

Animal Dancer

Noelle Boggio

Animal Dancer

Jordan Dawe

Animal Dancer

Alexandra Stapley

Taylor Wedell

Laura de Carteret

Mrs. Wedell

Nicole Crimi

Kylie George

Erin Norah Thompson

Dawn Schweitzer

Dan Willmott

Mr. George

Michelle Hoffman

Kissing Girl

Valerie Casault

Kissing Girl

Sharron Matthews

Joan

Jo Chim

Salesperson

Randi Lee Butcher

Skater Girl

Erin Jarvis

Skater Girl

Kaylen Christensen

Jock Girl

Jill Morrison

Crying Girl

David Sazant

Marymount Captain

Clare Preuss

Caroline Krafft

Bruce Hunter

Mathlete Moderator

Megan Millington

Junior Plastic

Tara Shelley

Junior Plastic

Shannon Todd

Junior Plastic

David Reale

Glenn Coco (uncredited)

Krysta Carter

Wannabe (uncredited)