Kadro (31)
Forrest J. AckermanForreyEric BennettPhil RockwellKaroline BrandtTina RockwellBill ButtsGraine
Kurt CarleySurgeon General 2
Bill CorsoCreator (voice)
Warwick DavisPlatesJohn DeallJohnNeil DooleyPig PenJason DugreBrainRuta EmpakerisSecretaryBevis FavershamBevis
Joel HarlowOctobaby
Peter Iasillo Jr.PeteyPhilip JonesSalmonLee KocielaMatthew RockwellJoe LittleBig JoeLiz LittleGrannyClayton MartinezClayJim O'DonoghueThe SheriffLes PollackJedAllen RichardShakes'Headless' SeanCreatorAaron SimsSurgeon General 1Geraldine StoneMiss M.I.A.TonopahSidecar Dog
Alan TuskesBig AlLinda WeinribGloria Jean RockwellBen WilliamsBabyLittle WillyStrangled FelineMona MarksAdditional Voice Over (voice)