Kadro (33)
Tim CurryYegor (voice)
Robert PatrickLouie (voice)
Kelly RipaNat's Mom (voice)
Trevor GagnonNat (voice)
Philip BoldenI.Q. (voice)
Nicollette SheridanNadia (voice)
Ed Begley Jr.Poopchev (voice)
David GoreScooter (voice)
Christopher LloydAmos (voice)
Adrienne BarbeauScooters Mom (voice)
Buzz AldrinHimself
Eddie FriersonCommander Aldrin
David CowgillCommander CollinsSteven KramerLeonideSophie SimpsonKatie (voice)Sandy SimpsonCommander Armstrong (voice)
Phil ProctorSenior Official (voice)
Lloyd SherrMission Control 1969 (voice)
Nicholas GuestFly Buddy #1 (voice)
Archie HahnFly Buddy #2
Lynnanne ZagerFly at Launch (voice)
Scott MenvilleButch (voice)
Michael McConnohieAmerican Newscaster (voice)Doug StoneRussian Newscaster (voice)
Doug StoneRussian Newscaster (voice)
Jessica Gee-GeorgeMaggot #1 (voice)
Mona MarshallMaggot #2 (voice)
Barbara GoodsonMaggot #3 (voice)
Gregg BergerPale Russian Fly (voice)
Grant GeorgePale Russian Fly (voice)Dean WeinAdditional Voices (voice)
Melora HarteAdditional Voices (voice)
Max BurkholderMom's Maggot (voice)